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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia.

contains the active ingredient fluconazole

What is in this leaflet

This leaflet answers some common questions about DIZOLE ONE.
It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have benefits and risks.Your doctor or pharmacist has weighed the risks of you taking DIZOLE ONE against the benefits expected for you.
If you have any concerns about taking this medicine, talk to your doctor or pharmacist.
Keep this leaflet with your medicine.
You may need to read it again.
The information in this leaflet relates only to DIZOLE ONE.It is not to be used in relation to any other product, which may also contain the same active ingredient.

What DIZOLE ONE is used for

DIZOLE ONE is used to treat a type of fungal infection called vaginal thrush.
DIZOLE ONE contains the active ingredient fluconazole, which belongs to a group of medicines called azole antifungals.These medicines work by preventing the growth of these fungi causing your infection.

What is vaginal thrush

Vaginal thrush is a common name for vaginal candidiasis, generic toradol best price no prescription an infection caused by a yeast-like fungus called Candida.
Candida is one of many organisms that live in the vagina.Your body’s natural balance (immune system) normally keeps Candida under control, but when this natural balance is upset, Candida can multiply and can cause thrush symptoms.
Common symptoms of vaginal thrush include:
itching, burning or soreness around the vagina
cottage-cheese like discharge
swelling or irritation of the infected area.
Things that may help you to avoid thrush in the future:
wear cotton briefs, stockings and loose-fitting clothing rather than tight synthetic clothing
wash regularly, but do not wash and dry yourself harshly
avoid perfumed soaps, bath additives and vaginal deodorants.
Your doctor or pharmacist may have more information on things you can do to avoid thrush in the future.
Ask your doctor if you have any questions about why this medicine has been prescribed for you.
Your doctor may have prescribed it for another reason.
There is no evidence that DIZOLE ONE is addictive.
DIZOLE ONE is a “Pharmacist Only Medicine”.It is available without a doctor’s prescription but your pharmacist’s advice is required.
DIZOLE ONE is not recommended for children under 18 years of age except under doctor supervision.

Before you take DIZOLE ONE

When you must not take it

Do not take DIZOLE ONE if you have an allergy to:
any medicine containing fluconazole
any other azole antifungals related to fluconazole such as miconazole (eg. Daktarin), ketoconazole (eg. Nizoral), clotrimazole (eg. Canestan, Clonea), or itraconazole (Sporanox)
any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include
shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin
Do not take DIZOLE ONE if you are taking
cisapride (Prepulsid), a medicine used to treat stomach problems
Combining DIZOLE ONE with the above medicines may cause serious side effects such as an abnormal heart rhythm.
Do not take DIZOLE ONE if you are pregnant, suspect you may be pregnant or if you may become pregnant during treatment.
It may affect your developing baby if you take it during pregnancy.
Do not take DIZOLE ONE if you are breastfeeding.
The active ingredient in DIZOLE ONE passes into breast milk and there is a possibility that your baby may be affected.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor or pharmacist.

Before you start to take it

Tell your doctor or pharmacist if you have allergies to any other medicines, foods, dyes or preservatives.
Tell your doctor or pharmacist if you have or have had any of the following medical conditions:
thrush more than twice in the last six months
liver problems
kidney problems
heart problems
HIV infection or AIDS.
Your doctor or pharmacist may want to take special care if you have any of these conditions.
Tell your doctor or pharmacist before using DIZOLE ONE if you are taking warfarin (eg. Marevan, Coumadin), as bleeding or bruising may occur.
If you have not told your doctor or pharmacist about any of the above, tell him/her before you start taking DIZOLE ONE.

Taking other medicines

Do not take DIZOLE ONE if you are taking
cisapride (Prepulsid), a medicine used to treat stomach problems
Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines and DIZOLE ONE may interfere with each other.These include:
warfarin (eg. Marevan, Coumadin), a medicine used to prevent blood clots
phenytoin (e.g. Dilantin) or carbamazepine (e.g. Tegretol), medicines used to treat epilepsy
cyclosporin (ciclosporin) (eg. Neoral), sirolimus (eg. Rapamune) or tacrolimus (eg. Prograf), medicines used to prevent organ transplant rejection or to treat certain problems with the immune system
certain medicines use to treat diabetes such as:
glibenclamide (eg. Daonil, Glimel), glipizide (eg. Minidiab, Melizide), glimepiride (eg. Amaryl), gliclazide (eg. Diamicron, Glyade)
pioglitazone (eg. Actos), rosiglitazone (eg. Avandia)
rifampicin (eg. Rifadin, Rimycin) or rifabutin (eg. Mycobutin), antibiotics used to treat infections
theophylline (eg. Nuelin), a medicine used to treat asthma
midazolam (eg. Hypnovel) and triazolam (eg. Halcion), medicines used as sedatives or to treat anxiety
zidovudine (eg. Retrovir), saquinavir (e.g. Invirase), medicines used to treat AIDS patients
hydrochlorothiazide (eg. Dithiazide), a medicine used for treating fluid problems and high blood pressure
the contraceptive pill (birth control pill)
amphotericin B (amphotericin) (eg. Fungilin), a medicine used to treat fungal infection
erythromycin (eg. E-Mycin) and azithromycin (e.g. Zithromax), antibiotics used to treat certain types of bacterial infections
anticancer drugs such as cyclophosphamide monohydrate, vincristine and vinblastine, medicines used to treat certain types of cancers
carbamazepine (eg. Tegretol), a medicine used in the treatment of epilepsy and bipolar disorder
NSAIDS such as naproxen, diclofenac and celecoxib (eg. Celebrex)
opioid pain killers such as alfentanil, fentanyl and methadone
losartan, a medicine used to treat high blood pressure
cimetidine, a medicine used to relieve heartburn and indigestion
calcium channel blockers, such as nifedipine, amlodipine and felodipine used in relieving high blood pressure and certain heart conditions
statins such as atorvastatin, simvastatin and fluvastatin, used to control high cholesterol levels
antidepressants such as amitriptyline (eg. Endep) and nortriptyline.
Talk to your doctor about the need for an additional method of contraception while taking DIZOLE ONE.
DIZOLE ONE may decrease the effectiveness of some birth control pills.
Your doctor can tell you what to do if you are taking any of these medicines.
These medicines may be affected by DIZOLE ONE or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.

How to take DIZOLE ONE

Follow all directions given to you by your doctor and pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist for help.

How much to take

For vaginal thrush in adults, only a single dose (1 capsule) of DIZOLE ONE is needed.
Do not give DIZOLE ONE to children under 18 years of age except under doctor supervision.

How to take it

Swallow the capsule whole with a glass of water.
DIZOLE ONE can be taken with or without food.

If you take too much (overdose)

Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much DIZOLE ONE. Do this even if there are no signs of discomfort or poisoning.
You may need urgent medical attention.

While you are taking DIZOLE ONE

Things you must do

If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking DIZOLE ONE
Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine.
Use effective contraception to prevent pregnancy while taking DIZOLE ONE.
If you become pregnant while taking this medicine, tell your doctor immediately.
If your symptoms do not improve after 3 days, tell your doctor or pharmacist.

Things you must not do

Do not take DIZOLE ONE to treat any other complaints unless your doctor or pharmacist tells you to.
Do not give your medicine to anyone else, even if they have the same condition as you.

Things to be careful of

Tell your doctor immediately if you develop a rash while taking DIZOLE ONE.
People with HIV, AIDS or a weak immune system may be more prone to serious side effects of the skin.
Be careful when driving vehicles or operating machinery as occasional dizziness or seizures may occur.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking DIZOLE ONE.
This medicine helps most people and is generally well tolerated.However it may have unwanted side effects in some people.
All medicines can have side effects.Sometimes they are serious, most of the time they are not.You may need medical treatment if you get some of the side effects.
Do not be alarmed by the following list of possible side effects.
You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
nausea (feeling sick), vomiting
stomach pain, indigestion
The above list includes the more common side effects of your medicine. They are usually mild and short-lived.
Tell your doctor as soon as possible if you notice any of the following:
unusual muscle stiffness causing poor control of movement
signs of frequent or worrying infections such as fever, severe chills, sore throat or mouth ulcers
swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing
asthma, wheezing, shortness of breath
sudden or severe itching, skin rash, hives
fainting, seizures or fits
flaking of the skin
yellowing of the skin or eyes, also called jaundice
bleeding or bruising more easily than normal, reddish or purplish blotches under the skin
passing more urine than normal, kidney pain (pain on the sides of the body)
symptoms of liver disease such as yellowing of the skin or eyes; dark urine, pale stools; loss of appetite; unusual tiredness
irregular heart beat or palpitations
increased sweating.
The above list includes serious side effects that may require medical attention.Serious side are rare.
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people.

After taking DIZOLE ONE


Keep your capsules in the pack until it is time to take them.
If you take the capsules out of the pack they may not keep well.
Keep your capsule in a cool dry place where the temperature stays below 25°C.
Do not store DIZOLE ONE or any other medicine in the bathroom or near a sink.Do not leave it on a window sill or in the car.
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.


If your doctor or pharmacist tells you to stop taking this medicine or it’s the expiry date has passed, ask your pharmacist what to do with it.

Product description

What it looks like

DIZOLE ONE is a hard white gelatin capsule, marked with “G” and “FC 150” in black ink.
Each pack contains 1 capsule.


The active ingredient in DIZOLE ONE is fluconazole 150 mg.
Each capsule also contains the following inactive ingredients:
lactose monohydrate
maize starch
silicon dioxide
magnesium stearate
sodium lauryl sulfate
titanium dioxide (E171)
TekPrint SW-9008 Black Printing Ink
TekPrint SW-9009 Black Printing Ink.
Dizole One contains sulfites and sugars (as lactose).


DIZOLE ONE is supplied in Australia by:
Alphapharm Pty Ltd
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point NSW 2000
Phone: (02) 9298 3999
Medical Information
Phone: 1800 028 365
Australian registration number:
This leaflet was prepared on
20 December 2019.

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